EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.1.1.59 | S-adenosyl-L-homocysteine | - |
Saccharomyces cerevisiae |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.1.1.59 | 0.04 | - |
S-adenosyl-L-methionine | - |
Saccharomyces cerevisiae | |
2.1.1.59 | 1.33 | - |
[cytochrome c]-L-lysine | of horse heart | Saccharomyces cerevisiae |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.1.1.59 | 97000 | - |
gel filtration | Saccharomyces cerevisiae |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.1.59 | S-adenosyl-L-methionine + cytochrome c L-lysine | Saccharomyces cerevisiae | in vivo methylation of cytochrome c in yeast occurs probably before cytochrome c is attached to the mitochondria | S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine | - |
? | |
2.1.1.59 | S-adenosyl-L-methionine + cytochrome c L-lysine | Saccharomyces cerevisiae | regulation of enzyme and cytochrome c substrate is not in parallel manner | S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.1.1.59 | Saccharomyces cerevisiae | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.1.1.59 | partially | Saccharomyces cerevisiae |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.1.1.59 | 0.000117 | - |
partially purified enzyme | Saccharomyces cerevisiae |
EC Number | Storage Stability | Organism |
---|---|---|
2.1.1.59 | -20°C, pH 7.0, crude extract supernatant, stable | Saccharomyces cerevisiae |
2.1.1.59 | purified enzyme is stabilized by addition of 66% ammonium sulfate during storage | Saccharomyces cerevisiae |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.1.59 | S-adenosyl-L-methionine + cytochrome c L-lysine | specific for unmethylated cytochrome c | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine | a single lysine residue at position 72 of horse heart cytochrome c is methylated | ? | |
2.1.1.59 | S-adenosyl-L-methionine + cytochrome c L-lysine | specific for unmethylated cytochrome c | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine | 9:17:74 | ? | |
2.1.1.59 | S-adenosyl-L-methionine + cytochrome c L-lysine | specific for unmethylated cytochrome c | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine | mixture of epsilon-N-monomethyllysine, epsilon-N-dimethyllysine and epsilon-N-trimethyllysine in the ratio 1:3:4 | ? | |
2.1.1.59 | S-adenosyl-L-methionine + cytochrome c L-lysine | horse heart cytochrome c-72 | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine | a single lysine residue at position 72 of horse heart cytochrome c is methylated | ? | |
2.1.1.59 | S-adenosyl-L-methionine + cytochrome c L-lysine | horse heart cytochrome c-72 | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine | 9:17:74 | ? | |
2.1.1.59 | S-adenosyl-L-methionine + cytochrome c L-lysine | horse heart cytochrome c-72 | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine | mixture of epsilon-N-monomethyllysine, epsilon-N-dimethyllysine and epsilon-N-trimethyllysine in the ratio 1:3:4 | ? | |
2.1.1.59 | S-adenosyl-L-methionine + cytochrome c L-lysine | overview: substrate activity of various cytochromes c | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine | a single lysine residue at position 72 of horse heart cytochrome c is methylated | ? | |
2.1.1.59 | S-adenosyl-L-methionine + cytochrome c L-lysine | overview: substrate activity of various cytochromes c | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine | 9:17:74 | ? | |
2.1.1.59 | S-adenosyl-L-methionine + cytochrome c L-lysine | overview: substrate activity of various cytochromes c | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine | mixture of epsilon-N-monomethyllysine, epsilon-N-dimethyllysine and epsilon-N-trimethyllysine in the ratio 1:3:4 | ? | |
2.1.1.59 | S-adenosyl-L-methionine + cytochrome c L-lysine | in vivo methylation of cytochrome c in yeast occurs probably before cytochrome c is attached to the mitochondria | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine | - |
? | |
2.1.1.59 | S-adenosyl-L-methionine + cytochrome c L-lysine | regulation of enzyme and cytochrome c substrate is not in parallel manner | Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine | - |
? | |
2.1.1.59 | S-adenosyl-L-methionine + [cytochrome c]-L-lysine | - |
Saccharomyces cerevisiae | S-adenosyl-L-homocysteine + [cytochrome c]-N6-methyl-L-lysine | - |
r |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.1.1.59 | 9 | - |
- |
Saccharomyces cerevisiae |